Nature

Public platform with 39,472 exome control samples enables association studies without genotype sharing

Acquiring a sufficiently powered cohort of control samples matched to a case sample can be time-consuming or, in some cases, impossible. Accordingly, an ability to leverage genetic data from control ...
Nature

Exome sequencing analysis of Japanese autism spectrum disorder case-control sample supports an increased burden of synaptic function-related genes

Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by deficits in social interactions and repetitive behaviors manifesting in early childhood [1]. Little is known regarding ...
Medscape

INTERHEART: A Global Case-Control Study of Risk Factors for Acute Myocardial Infarction

Whereas cardiovascular disease-related mortality has declined in most developed countries, its known prevalence is increasing worldwide, although few data on the causes of heart disease in the ...
MedPage Today on MSN

JAMA Journal Publishes COVID Vaccine Study Squelched by CDC Leader

Bhattacharya attacked study's test-negative design, a staple of vaccine effectiveness rese ...
ascopubs.org

A Simple Cervicovaginal Epigenetic Test for Screening and Rapid Triage of Women With Suspected Endometrial Cancer: Validation in Several Cohort and Case/Control Sets

Effectiveness of Intensive Versus Minimalist Follow-Up Regimen on Survival in Patients With Endometrial Cancer (TOTEM Study): A Randomized, Pragmatic, Parallel Group, Multicenter Trial We developed a ...