Background Fibrosis and tumour innervation are two features of the tumour microenvironment (TME) that contribute directly to ...
I read the GOULASH trial with great interest. This multicentre, double-blind randomised clinical trial compared early high-energy enteral nutrition (30 kcal/kg/day) with a gradually increasing energy ...
Background Clinicians use fibrosis in a liver biopsy to predict clinical outcomes of chronic liver disease. The performance of non-invasive tests has been evaluated against histological assessment of ...
Background Sympathetic signalling plays a critical role in the initiation and progression of various malignancies. However, its specific contribution to intrahepatic cholangiocarcinoma (iCCA) remains ...
Correspondence to: Professor J Dent Department of Gastroenterology, Hepatology, and General Medicine, Level 7, North Wing, North Terrace, Royal Adelaide Hospital, Adelaide, South Australia 5000, ...
3 Department of Clinical and Experimental Medicine, Division of Pediatrics, Linköping University, Linköping, Sweden 4 Department of Clinical and Experimental Medicine, Division of Inflammation ...
Objective We performed a meta-analysis of observational studies to quantify the magnitude of the association between non-alcoholic fatty liver disease (NAFLD) and risk of extrahepatic cancers. Design ...
Background: Patients with irritable bowel syndrome (IBS) often feel they have some form of dietary intolerance and frequently try exclusion diets. Tests attempting to predict food sensitivity in IBS ...
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Afferent fibres convey sensory information from the upper gastrointestinal tract to the central nervous system but the nature of this information is different for vagal and spinal pathways. Vagal ...
Background Despite the long-standing recommendations of high-protein diets for patients with cancer, the precise mechanisms of this dietary approach in benefiting tumour suppression and enhancing ...
The aim of this study was to establish the relative importance of risk factors for mortality after acute upper gastrointestinal haemorrhage, and to formulate a simple numerical scoring system that ...
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