Multiple sclerosis is a condition whereby the immune system attacks and destroys myelin – the protective coating of nerve fibers – which triggers movement problems characteristic of the disease. Now, ...

In long-lived animals, renewed but thin myelin sheaths are enough to restore the impaired nervous system and can do so for years after the onset of disease, scientists have discovered. In the central ...

When treated with a novel protein function inhibitor called ESI1, mice that mimic the symptoms of multiple sclerosis (MS) and lab-prepared human brain cells both demonstrated the ability to regenerate ...

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Scientists at the University of Rochester Medical Center (URMC) have demonstrated how human glial progenitor cells (hGPCs) transplanted into animal models of multiple sclerosis, and other white matter ...

How oligodendrocytes use fatty acid metabolism as an energy reserve to maintain axonal function and myelin stability when glucose is scarce, offering insights into neurodegenerative disease mechanisms ...

A research team led by neurobiologist Professor Claire Jacob has identified an important mechanism that can be used to control the restoration of myelin sheaths following traumatic injury and in ...

We recruited first-episode patients (FEP) from outpatient, inpatient, and emergency room settings at The University of Alabama at Birmingham (UAB). After being deemed to have capacity to give consent ...

Vesicular release from neurons promotes myelin sheath growth on axons. Oligodendrocytes express proteins that allow dendrites to respond to vesicular release at synapses, suggesting that axon-myelin ...

Efficient removal of abnormal myelin allows survival of nerve fibers targeted by adaptive immune cells, according to a novel study. Myelin is an insulating sheath around axons -- the processes ...

Neurons are the basic functional units of the brain. They have three main parts: dendrites, a cell body, and an axon (more commonly known as a nerve fiber). Dendrites look like twigs growing off the ...

In the central nervous system of humans and all other mammals, a vital insulating sheath composed of lipids and proteins around nerve fibers helps speed the electrical signals or nerve impulses that ...