For almost a century, budding neuroscientists have been taught that the headband-like strip of brain tissue over our ears that controls our movements, called the motor cortex, contains an orderly map ...

Compared to other animal species, humans can plan and execute highly sophisticated motor tasks, including the ability to write complex characters using their hands. While many past studies have tried ...

We present a quantitative strategy to identify all projection neuron types from a given region with statistically different patterns of anatomical targeting. We first validate the technique with mouse ...

Researchers have discovered that the dorsal premotor cortex serves a 'meta-learning' function, overseeing and regulating physical movements. Once believed to be limited to movement planning, this ...

Cytoplasmic TDP-43 pathology is a pathological sign of ALS/ALS-FTD and a converging disease event across different genotypes, phenotypes and CNS areas. To understand this process and target it ...

Your nerves transmit messages within the brain, as well as among the brain, spinal cord, and the body. In order to do this, they use a combination of electrical and chemical signaling. Motor neurons ...