Innovative Bifunctional Fusion Protein ATG-207 Shows Promise For Autoimmune Disease Treatment

Conclusion: ATG-207 represents a differentiated immune tolerance–restoring strategy that integrates precision T cell ...

Antengene Presented First Preclinical Data at EULAR 2026 Showing ATG-207 Promotes Regulatory T Cell Induction and Immune Tolerance

Antengene Corporation Limited ("Antengene", SEHK: 6996.HK) , a leading innovative, commercial-stage global biotech company ...
Malaysia Sun

Antengene to Present First Preclinical Data on ATG-207 (CD3-TGF- Bifunctional Fusion Protein) at EULAR 2026

Antengene Corporation Limited ("Antengene", SEHK: 6996.HK) , a leading innovative, commercial-stage global biotech company dedicated to discovering, developing and commercializing first-in-class ...
BioWorld

Aptevo adds Nectin-4 x CD3 bispecific T-cell engager to pipeline

Aptevo Therapeutics Inc. has added a preclinical candidate, APVO-455, to its portfolio of CD3-directed candidates built on the CRIS-7-derived CD3 binding domain.
The American Journal of Managed Care

Study Identifies Key Predictors of Successful CD3+ Cell Apheresis for CAR T Manufacturing in DLBCL

Machine-learning analysis identifies factors predicting T cell collection efficiency in CAR T-cell therapy for DLBCL patients. Higher blood volume, not higher circulating T-cell numbers, correlates ...
EurekAlert!

Study reveals persistent CD3+ T-cell decrease linked to higher mortality in elderly patients with sepsis

A new study published online in the Journal of Intensive Medicine on June 17, 2025, highlights early and dynamic alterations in lymphocyte subsets following sepsis in elderly patients and their ...
Medical Xpress

Scientists track real-time signaling in T cell activation to show how the immune system defends against threats

T cell activation—the process by which these key immune defenders recognize threats and mobilize against them—depends on exquisitely timed molecular signals. Now researchers have captured one of the ...
News Medical

Mitochondria and lysosomes work together to control regulatory T cell activation

Metabolism guides the activation states of regulatory T cells, the immune cells that prevent inappropriate activation of the immune system. St. Jude Children's Research Hospital scientists recently ...